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Reliable-1 Tussin

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Active ingredient
Guaifenesin 100 mg/5 mL
Other brand names
Drug class
Expectorant
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
January 2, 2026
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Guaifenesin 100 mg/5 mL
Other brand names
Drug class
Expectorant
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
January 2, 2026
Manufacturer
RELIABLE 1 LABORATORIES LLC
Registration number
M012
NDC root
69618-068
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Tussin is a medication designed to help you manage coughs by loosening phlegm (mucus) and thinning bronchial secretions. This action makes your coughs more productive, allowing you to clear mucus from your airways more effectively. If you're dealing with a cough that comes with congestion, Tussin can be a supportive option to help you feel more comfortable.

Uses

This medication is designed to help you breathe easier by loosening phlegm (mucus) in your airways. By doing so, it makes your coughs more productive, allowing you to clear out mucus more effectively. If you're dealing with respiratory issues, this can be a helpful option to consider for improving your comfort and breathing.

Dosage and Administration

When using this medication, it's important to follow the dosing instructions carefully to ensure your safety and effectiveness. For adults and children over 12 years of age, you should take 2 teaspoonfuls (which is 10 milliliters) every 4 hours as needed, or as directed by your doctor. Make sure to measure the dose using the dosing cup provided, as this will help you get the correct amount.

Remember, you should not take more than 6 doses in any 24-hour period. If you are considering this medication for children under 12 years of age, please do not use it, as it is not recommended for that age group. Always consult with a healthcare professional if you have any questions or concerns about using this medication.

What to Avoid

It's important to be aware of certain precautions when using this medication. While there are no specific contraindications or concerns about abuse, misuse, or dependence (which means relying on a substance in a harmful way), you should take care to follow the instructions provided.

If you suspect an overdose, it’s crucial to seek medical help immediately or contact a Poison Control Center. Your safety is the top priority, so always use the medication as directed and reach out for assistance if needed.

Side Effects

If you are considering using this medication, it's important to consult your doctor first if you have a cough that produces a lot of mucus or if your cough is chronic, which can happen with conditions like smoking, asthma, chronic bronchitis, or emphysema.

You should stop using the medication and seek medical advice if your cough lasts more than 7 days, returns after improvement, or is accompanied by symptoms such as fever, rash, or a persistent headache, as these may indicate a more serious health issue.

Warnings and Precautions

Before using this medication, it's important to consult your doctor if you have a cough that produces a lot of phlegm (mucus) or if your cough is chronic, which can happen with conditions like smoking, asthma, chronic bronchitis, or emphysema.

If your cough lasts more than 7 days, returns, or is accompanied by symptoms such as fever, rash, or a persistent headache, you should stop using the medication and contact your doctor, as these could indicate a more serious health issue.

In the event of an overdose, seek emergency medical help or contact a Poison Control Center immediately. Your health and safety are paramount, so please take these precautions seriously.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's always important to be aware of the signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, you should contact your local emergency services or go to the nearest hospital right away. Having the medication packaging or information on hand can help medical professionals provide the best care. Always remember that when it comes to medications, it's better to be safe and get help if you have any concerns.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

It is important to note that this medication should not be used in children under 12 years of age. If you are a parent or caregiver, please ensure that your child meets this age requirement before considering this treatment. Always consult with a healthcare professional if you have any questions or concerns about the appropriate use of this medication for your child.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult considering this medication, it’s important to consult with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken.

Always keep in mind that older adults may have different responses to medications, so discussing any concerns with a doctor is essential for ensuring safety and effectiveness.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

It's always best to discuss your individual situation with your healthcare provider, who can offer personalized advice and ensure that any medications you take are safe and appropriate for your kidney health.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may want to conduct regular liver function tests (which check how well your liver is working) to ensure your safety while using any medication.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the best quality and safety of your product, store it at room temperature. It's important to keep the bottle tightly closed when not in use to prevent contamination and maintain its effectiveness. Additionally, protect the product from light, as exposure can affect its quality. Once opened, please remember to discard the product to ensure your safety and the safety of others.

Additional Information

You should take this medication orally. For adults and children over 12 years of age, the recommended dose is 2 teaspoonfuls (10 mL) every 4 hours as needed or as directed by your doctor. However, this medication is not recommended for children under 12 years of age, so please avoid using it for that age group.

FAQ

What is Tussin used for?

Tussin helps loosen phlegm (mucus) and thins bronchial secretions to make coughs more productive.

What is the recommended dosage for adults and children over 12?

Adults and children over 12 years of age should take 2 teaspoonfuls (10 mL) every 4 hours as needed or as directed by a doctor.

Are there any age restrictions for using Tussin?

Children under 12 years of age should not use Tussin.

What should I do in case of an overdose?

In case of overdose, get medical help or contact a Poison Control Center right away.

What should I do if my cough lasts more than 7 days?

Stop using Tussin and ask a doctor if your cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache.

Can I use Tussin if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before using Tussin.

How should I store Tussin?

Store Tussin at room temperature, keep the bottle tightly closed when not in use, and protect it from light.

Packaging Info

Below are the non-prescription pack sizes of Reliable-1 Tussin (guaifenesin). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Reliable-1 Tussin.
Details

Drug Information (PDF)

This file contains official product information for Reliable-1 Tussin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the facilitation of mucus clearance in patients with respiratory conditions. It helps to loosen phlegm and thins bronchial secretions, thereby enhancing the productivity of coughs.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children over 12 years of age are advised to take 2 teaspoonfuls (10 mL) every 4 hours as needed or as directed by a healthcare professional. It is imperative that no more than 6 doses are taken within a 24-hour period to avoid potential overdose.

For accurate dosing, the provided dosing cup must be used to measure the liquid. Children under 12 years of age should not use this medication.

Contraindications

There are no specific contraindications listed for this product. However, in the event of an overdose, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Warnings and Precautions

Patients should consult a healthcare professional prior to use if they have a cough characterized by excessive phlegm (mucus) or if they are experiencing a chronic cough associated with conditions such as smoking, asthma, chronic bronchitis, or emphysema.

In the event that a cough persists for more than 7 days, recurs, or is accompanied by symptoms such as fever, rash, or a persistent headache, it is imperative to discontinue use and seek medical advice. These symptoms may indicate the presence of a serious underlying condition that requires further evaluation.

In cases of suspected overdose, immediate medical assistance should be sought, or the local Poison Control Center should be contacted without delay.

Patients are advised to remain vigilant and to stop taking the medication if the aforementioned symptoms occur, and to promptly inform their healthcare provider for further assessment and guidance.

Side Effects

Patients should be advised to consult a healthcare professional prior to use if they have a cough accompanied by excessive phlegm (mucus) or if they experience a chronic cough, which may be indicative of underlying conditions such as smoking, asthma, chronic bronchitis, or emphysema.

In the event that a cough persists for more than 7 days, recurs, or is accompanied by symptoms such as fever, rash, or a persistent headache, patients are instructed to discontinue use and seek medical advice. These symptoms may signify a serious condition that requires further evaluation.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Reliable-1 Tussin (guaifenesin). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Reliable-1 Tussin.
Details

Pediatric Use

Pediatric patients under 12 years of age should not be administered this medication. Safety and efficacy have not been established in this age group, and use is contraindicated. Healthcare professionals are advised to consider alternative treatments for pediatric patients within this age range.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered in these populations to ensure the safety of both the mother and the fetus or infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

There is currently no specific information available regarding overdosage for this medication. Healthcare professionals are advised to monitor patients closely for any signs of adverse effects or symptoms that may arise from excessive dosing.

In the event of suspected overdosage, it is recommended that healthcare providers initiate supportive care and symptomatic treatment as necessary. Patients should be evaluated for potential complications, and appropriate interventions should be implemented based on clinical judgment.

For further guidance, healthcare professionals may refer to established protocols for managing drug overdosage or consult a poison control center.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. No specific non-teratogenic effects have been identified. Additionally, there are no detailed findings related to nonclinical toxicology or animal pharmacology and toxicology available.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. It is crucial to emphasize the importance of safety in the home environment, particularly for households with young children.

In the event of an overdose, healthcare providers should instruct patients to seek medical help immediately or contact a Poison Control Center. Patients should be made aware of the signs of overdose and the urgency of obtaining assistance to ensure their safety and well-being.

Storage and Handling

The product is supplied in a bottle that must be kept tightly closed when not in use to maintain its integrity. It should be stored at room temperature, away from direct light to protect it from degradation. It is important to discard the product after opening to ensure safety and efficacy.

Additional Clinical Information

The medication is administered orally. For adults and children over 12 years of age, the recommended dosage is 2 teaspoonfuls (10 mL) every 4 hours as needed or as directed by a healthcare professional. It is important to note that this medication is not recommended for use in children under 12 years of age.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experiences.

Drug Information (PDF)

This file contains official product information for Reliable-1 Tussin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Reliable-1 Tussin, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.