Up and up

Description

Up & Up Blemish Controlling Apricot Scrub is a topical formulation designed for the management of blemishes. The product is packaged in a net weight of 6 ounces (170 grams) and is identified by the National Drug Code (NDC) 11673-930-15.

Uses and Indications

This drug is indicated for the treatment of acne.

There are no teratogenic effects associated with this medication. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

The affected area should be covered with a thin layer of the medication and rinsed thoroughly. This application may be performed one to three times daily, depending on the severity of the condition and the patient's response to treatment.

In cases where bothersome dryness or peeling occurs, it is recommended to reduce the frequency of application to once daily or every other day. To minimize the risk of excessive drying of the skin, it is advisable to initiate treatment with one application daily. The frequency may then be gradually increased to two or three times daily as needed or as directed by a healthcare professional.

Contraindications

Use of this product is contraindicated in patients with a history of eye contact. In the event of contact with the eyes, it is imperative to flush thoroughly with water to mitigate potential irritation or injury. No other contraindications have been identified.

Warnings and Precautions

For external use only. It is imperative that healthcare professionals advise patients to avoid ingestion of the product. In the event of accidental swallowing, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Caution is advised regarding the concurrent use of this product with other topical acne medications. The likelihood of skin irritation and dryness increases when multiple topical agents are applied simultaneously. Should irritation occur, it is recommended that patients limit their use to one topical acne medication at a time to mitigate adverse effects.

Healthcare professionals should also instruct patients to avoid contact with the eyes. In the event of accidental contact, it is essential to flush the eyes thoroughly with water to prevent potential complications.

No specific laboratory tests are recommended for monitoring the use of this product.

Side Effects

For external use only. No specific adverse reactions or side effects have been reported in clinical trials or postmarketing experiences. Patients should be advised to use the product as directed and to consult a healthcare professional if any unexpected reactions occur.

Drug Interactions

The concurrent use of multiple topical acne medications may increase the risk of skin irritation and dryness. To mitigate this risk, it is advised that only one topical acne medication be used at a time. If irritation occurs, discontinuation of one of the medications is recommended to alleviate symptoms. Monitoring for signs of skin irritation is essential when initiating or adjusting treatment regimens involving topical acne therapies.

Packaging & NDC

Below are the non-prescription pack sizes of Up and up (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Geriatric Use

Elderly patients may not have specific information regarding the use of Up & Up Blemish Controlling Apricot Scrub, as the drug insert does not provide details on dosage adjustments, safety concerns, or special precautions for this population.

Healthcare providers should exercise caution when recommending this product to geriatric patients, considering the lack of data on its effects and safety profile in this age group. Monitoring for any adverse reactions or sensitivities is advisable, given the potential for altered skin sensitivity and other age-related changes in this demographic.

Pregnancy

There is currently no information available regarding the use of Up & Up Blemish Controlling Apricot Scrub during pregnancy. This includes any safety concerns, dosage modifications, or special precautions that may be necessary for pregnant patients. Healthcare professionals should exercise caution and consider the lack of data when advising women of childbearing potential regarding the use of this product during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available concerning the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.

It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.

In the event of an overdose, immediate medical attention should be sought. Healthcare providers should implement supportive care measures, which may include maintaining airway patency, providing supplemental oxygen, and monitoring vital signs.

Additionally, it is recommended to consult local poison control centers or toxicology experts for guidance on specific management protocols and interventions tailored to the situation.

Documentation of the incident, including the substance involved, estimated dose, and time of exposure, is crucial for effective management and follow-up care.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center if the medication is swallowed.

It is important to inform patients that the use of this medication in conjunction with other topical acne treatments may increase the likelihood of skin irritation and dryness. Therefore, if patients experience any irritation, they should be instructed to limit their use to one topical acne medication at a time.

Additionally, healthcare providers should emphasize the importance of avoiding contact with the eyes. In the event of accidental contact, patients should be instructed to flush the eyes thoroughly with water to mitigate any potential irritation.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. Proper handling should be observed to ensure optimal conditions are met throughout the storage period.

Additional Clinical Information

Patients should apply a thin layer of the product to the entire affected area and rinse thoroughly one to three times daily. If bothersome dryness or peeling occurs, the frequency of application should be reduced to once a day or every other day. To minimize the risk of excessive skin drying, it is advisable to start with one application daily and gradually increase to two or three times daily as needed or as directed by a clinician.

Drug Information (PDF)

This file contains official product information for Up and up, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)