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Active ingredient
Salicylic Acid 20 mg/1 mL
Other brand names
Dosage form
Liquid
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2013
Label revision date
October 14, 2024
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Salicylic Acid 20 mg/1 mL
Other brand names
Dosage form
Liquid
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2013
Label revision date
October 14, 2024
Manufacturer
TARGET CORPORATION
Registration number
M006
NDC root
11673-024
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

This medication is used for the treatment of acne, a common skin condition that can cause pimples, blackheads, and other blemishes. It works to help reduce the severity of acne, promoting clearer skin and improving your overall complexion. If you're struggling with acne, this treatment may be a helpful option to consider in your skincare routine.

Uses

If you're dealing with acne, this medication is designed specifically to help treat this common skin condition. Acne can be frustrating, but with the right treatment, you can see improvements in your skin's appearance and health.

It's important to note that this medication does not have any known teratogenic effects, meaning it does not cause birth defects. Additionally, there are no reported nonteratogenic effects, which means it doesn't have harmful effects that aren't related to birth defects either. Always consult with your healthcare provider for personalized advice and treatment options.

Dosage and Administration

To use this medication effectively, start by applying a thin layer to the entire affected area. You should rinse it off thoroughly one to three times a day, depending on your needs and how your skin reacts. If you notice any bothersome dryness or peeling, it’s a good idea to cut back on how often you apply it—try using it just once a day or even every other day.

Since this medication can sometimes cause excessive drying of the skin, it’s best to begin with one application daily. If your skin tolerates it well, you can gradually increase the frequency to two or three times a day, but only if needed or as your doctor advises. Always pay attention to how your skin responds and adjust accordingly for the best results.

What to Avoid

It's important to take care when using this medication. You should avoid contact with your eyes; if this happens, make sure to flush your eyes thoroughly with water to prevent irritation or damage.

Currently, there are no specific contraindications, controlled substance classifications, or noted risks of abuse, misuse, or dependence associated with this medication. Always follow the instructions provided and consult with your healthcare provider if you have any questions or concerns.

Side Effects

It's important to note that this product is for external use only. While no specific side effects or adverse reactions have been reported, you should always be aware of how your body responds to any new treatment. If you experience any unusual reactions, it's best to consult with a healthcare professional.

Warnings and Precautions

This product is for external use only, so please avoid applying it to any areas other than your skin. If you are using another topical acne medication, be cautious, as this can increase the risk of skin irritation and dryness. If you experience irritation, it’s best to stop using one of the products to see if your skin improves. Also, be careful to keep the product away from your eyes; if it does get in your eyes, rinse them thoroughly with water.

In case of accidental swallowing, seek medical help immediately or contact a Poison Control Center. There are no specific laboratory tests required for this product, but always stay alert to how your skin reacts and consult your doctor if you have any concerns.

Overdose

If you suspect an overdose, it's important to stay calm and take immediate action. While there is no specific information available about the signs of overdose for this medication, general symptoms can include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these signs, or if you are unsure, seek medical help right away.

In case of an overdose, contact your local emergency services or go to the nearest hospital. It's always better to be safe and get checked by a healthcare professional if you have any concerns about your health. Remember, timely intervention can make a significant difference.

Pregnancy Use

It’s important to be cautious when considering the use of this product during pregnancy, as its safety has not been established. High doses or prolonged use of salicylic acid, a common ingredient in some medications, is not recommended during pregnancy due to potential risks to your developing baby.

If you are pregnant or planning to become pregnant, it’s essential to consult with your healthcare provider before using this product. They can help you understand the risks and determine the best course of action for your health and the health of your baby.

Lactation Use

If you are breastfeeding or planning to breastfeed, you can feel reassured that there are no specific warnings or recommendations regarding nursing mothers or lactation in the information provided. This means that, based on the available data, there are no known risks associated with breastfeeding while using this medication.

However, it's always a good idea to consult with your healthcare provider about any medications you are taking to ensure they are safe for you and your baby. Your healthcare provider can give you personalized advice based on your specific situation.

Pediatric Use

It's important to keep this medication out of reach of children to prevent accidental ingestion. If your child swallows any of it, seek medical help immediately or contact a Poison Control Center for guidance. Taking these precautions can help ensure your child's safety.

Geriatric Use

While there is no specific information about the use of Up & Up Acne Wash (salicylic acid liquid) in older adults, it’s important to approach any new treatment with caution. Since the drug insert does not mention dosage adjustments or safety concerns for elderly patients, you should consult with a healthcare provider before starting this product. They can help ensure that it’s appropriate for your needs and discuss any potential interactions with other medications you may be taking. Always prioritize your health and safety when considering new skincare products.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective for your specific condition. They can help you understand any necessary precautions or adjustments based on your kidney health.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to be cautious when using multiple acne treatments at the same time. If you apply another topical acne medication along with this one, you may experience increased skin irritation and dryness. To minimize these side effects, it's best to use only one topical acne medication at a time.

Always discuss your current medications and any new treatments with your healthcare provider. They can help you understand the best approach for your skin care routine and ensure that you avoid any unnecessary discomfort.

Storage and Handling

To ensure safe handling and storage of the product, be aware that it may stain some fabrics. It's important to keep it away from clothing and other materials that could be affected. Always handle the product with care to avoid any spills or accidents that could lead to staining. If you do come into contact with fabric, act quickly to clean the area to minimize any potential marks.

For best results, store the product in a cool, dry place, away from direct sunlight and extreme temperatures. This will help maintain its effectiveness and safety for use. Always follow any additional instructions provided with the product for optimal handling and storage.

Additional Information

When using this medication, apply a thin layer to the entire affected area and rinse thoroughly one to three times a day. If you experience bothersome dryness or peeling, reduce your application to once a day or every other day. To avoid excessive drying of the skin, it's best to start with one application daily and gradually increase to two or three times daily as needed or as directed by your doctor.

FAQ

What is this drug used for?

This drug is used for the treatment of acne.

How should I apply this medication?

You should cover the entire affected area with a thin layer and rinse thoroughly one to three times daily.

What should I do if I experience dryness or peeling?

If you experience bothersome dryness or peeling, reduce application to once a day or every other day.

Are there any contraindications for this drug?

There are no contraindications listed for this drug.

Is this drug safe to use during pregnancy?

The safety of this product during pregnancy has not been established, and high doses or prolonged use of salicylic acid is contraindicated.

What precautions should I take while using this medication?

Avoid contact with eyes; if contact occurs, flush thoroughly with water. It's also advised to use only one topical acne medication at a time to minimize skin irritation.

What should I do if I accidentally swallow this medication?

If swallowed, get medical help or contact a Poison Control Center right away.

Can this medication stain fabric?

Yes, this medication may stain some fabric.

Is there any specific information for nursing mothers?

There are no specific warnings or recommendations regarding nursing mothers provided in the text.

Packaging Info

Below are the non-prescription pack sizes of Up and up (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up.
Details

Drug Information (PDF)

This file contains official product information for Up and up, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

The product is identified by the SPL code 34089-3. No specific description details are provided in the text.

Uses and Indications

This drug is indicated for the treatment of acne.

There are no teratogenic effects associated with this medication. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

The affected area should be covered with a thin layer of the medication and rinsed thoroughly. This application may be performed one to three times daily, depending on the severity of the condition and the patient's response to treatment.

In cases where bothersome dryness or peeling occurs, it is recommended to reduce the frequency of application to once daily or every other day. To minimize the risk of excessive drying of the skin, it is advisable to initiate treatment with one application daily. The frequency may then be gradually increased to two or three times daily as needed or as directed by a healthcare professional.

Contraindications

Use is contraindicated in patients with a history of eye contact, as exposure may lead to irritation. In the event of contact with the eyes, it is essential to flush thoroughly with water to mitigate potential adverse effects. No other contraindications have been identified.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients to avoid simultaneous use of this product with other topical acne medications, as this may increase the likelihood of skin irritation and dryness. In the event of irritation, it is recommended that patients discontinue the use of all topical acne treatments and consult a healthcare provider.

Contact with the eyes should be strictly avoided. Should accidental contact occur, it is imperative to flush the eyes thoroughly with water to mitigate any potential adverse effects.

In cases of ingestion, immediate medical assistance should be sought, or the patient should contact a Poison Control Center without delay.

No specific laboratory tests are required for monitoring the safe use of this product. However, healthcare professionals should remain vigilant for any signs of adverse reactions in patients using this medication.

Side Effects

For external use only. No specific side effects or adverse reactions have been reported in clinical trials or postmarketing experiences.

Drug Interactions

The concurrent use of multiple topical acne medications may increase the risk of skin irritation and dryness. To mitigate this risk, it is advised that only one topical acne medication be used at a time. If irritation occurs, discontinuation of one of the medications is recommended to allow the skin to recover. Monitoring for signs of irritation is essential when initiating or adjusting treatment regimens involving topical acne therapies.

Packaging & NDC

Below are the non-prescription pack sizes of Up and up (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up.
Details

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Geriatric Use

There is no specific information regarding the use of Up & Up Acne Wash (salicylic acid liquid) in geriatric patients. The prescribing information does not provide details on dosage adjustments, safety concerns, or special precautions for elderly patients. Therefore, healthcare providers should exercise caution and consider individual patient factors when prescribing this product to geriatric patients, as the absence of specific data necessitates careful monitoring and assessment of treatment efficacy and safety in this population.

Pregnancy

The safety of this product during pregnancy has not been established. The use of salicylic acid in high doses or for prolonged periods is contraindicated in pregnancy due to potential risk to the fetus. Pregnant patients or those planning to become pregnant should consult a healthcare provider before using this product to discuss potential risks and benefits.

Lactation

There are no specific warnings or recommendations regarding nursing mothers or lactation in the provided text. Therefore, healthcare professionals should consider the absence of data when advising lactating mothers about the use of this medication. It is advisable to monitor breastfed infants for any potential effects, although no specific information is available.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in clinical trials for this medication. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be warranted based on clinical judgment.

Overdosage

In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.

It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.

In the event of an overdose, immediate medical attention should be sought. Healthcare providers should implement supportive care measures, which may include maintaining airway patency, providing supplemental oxygen, and monitoring vital signs.

Additionally, it is recommended to consult local poison control centers or relevant toxicology resources for guidance on specific management protocols and antidotes, if applicable.

Documentation of the incident, including the amount and timing of the substance taken, is crucial for effective treatment and follow-up care.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. In the event of swallowing the medication, patients should be instructed to seek medical help or contact a Poison Control Center immediately.

Patients should be made aware that using this medication in conjunction with other topical acne treatments may increase the likelihood of skin irritation and dryness. It is recommended that patients use only one topical acne medication at a time to minimize the risk of irritation.

Additionally, healthcare providers should emphasize the importance of avoiding contact with the eyes. If contact occurs, patients should be instructed to flush the eyes thoroughly with water to mitigate any potential irritation.

Storage and Handling

The product is supplied in configurations that may include various packaging options. It is important to note that the product has the potential to stain certain fabrics, and appropriate precautions should be taken during handling to prevent any unintended damage.

For optimal storage, the product should be kept in a controlled environment, away from direct sunlight and extreme temperatures. Specific temperature ranges for storage have not been provided; however, it is advisable to maintain a stable environment to ensure product integrity.

Care should be taken to handle the product with clean, dry hands or appropriate gloves to minimize the risk of staining and to maintain the quality of the product.

Additional Clinical Information

Patients should apply a thin layer of the product to the entire affected area and rinse thoroughly one to three times daily. If bothersome dryness or peeling occurs, the frequency of application should be reduced to once a day or every other day. To minimize the risk of excessive skin drying, it is advisable to start with one application daily and gradually increase to two or three times daily as needed or as directed by a clinician.

Drug Information (PDF)

This file contains official product information for Up and up, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Up and up, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.