Up and up

Description

Up & Up Deep Clean Toner is presented in a dosage form of a liquid solution, contained in an 8 fluid ounce (236.5 mL) bottle. The product is identified by the National Drug Code (NDC) 11676-936-11.

Uses and Indications

This drug is indicated for the treatment of acne.

There are no teratogenic or nonteratogenic effects mentioned associated with the use of this drug.

Dosage and Administration

Healthcare professionals are advised to ensure that the skin is thoroughly cleaned prior to the application of this product. The recommended administration involves applying a thin layer to the entire affected area one to three times daily.

To minimize the risk of excessive drying of the skin, it is recommended to initiate treatment with one application per day. Based on the patient's response and as directed by a physician, the frequency may be gradually increased to two or three times daily if necessary.

In cases where bothersome dryness or peeling occurs, it is advisable to reduce the frequency of application to once daily or every other day to alleviate these symptoms.

Contraindications

Use of this product is contraindicated in individuals with a known hypersensitivity to any of its components.

Contact with the eyes should be strictly avoided. In the event of accidental contact, it is imperative to flush the eyes thoroughly with water to mitigate potential irritation or injury.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients to seek emergency medical assistance immediately if the product is ingested. In such cases, contacting a Poison Control Center is recommended.

It is important to note that the concurrent use of this product with other topical acne medications may increase the risk of skin irritation and dryness. Therefore, if patients experience irritation, they should be instructed to limit their use to one topical acne medication at a time.

Healthcare providers should also emphasize the necessity of avoiding contact with the eyes. In the event of accidental contact, patients should be advised to flush the eyes thoroughly with water to mitigate any potential adverse effects.

No specific laboratory tests are recommended for monitoring during the use of this product.

Side Effects

Patients should be advised that the product is for external use only. There are no specific adverse reactions or side effects reported in clinical trials or postmarketing experiences beyond this warning. It is essential for participants to adhere to the recommended usage guidelines to minimize any potential risks associated with improper use.

Drug Interactions

The concurrent use of multiple topical acne medications may increase the risk of skin irritation and dryness. To mitigate this risk, it is advised that only one topical acne medication be used at a time. If irritation occurs, discontinuation of additional topical agents is recommended to allow the skin to recover. Monitoring for signs of irritation is essential when initiating or adjusting treatment regimens involving topical acne therapies.

Packaging & NDC

Below are the non-prescription pack sizes of Up and up (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Geriatric Use

There is no specific information regarding the use of Up & Up Deep Clean Toner in geriatric patients. The prescribing information does not provide details on dosage adjustments, safety concerns, or special precautions that may be necessary for elderly patients. Therefore, healthcare providers should exercise caution and consider individual patient factors when recommending this product to geriatric patients, as the absence of specific data necessitates careful monitoring and assessment of the patient's response to treatment.

Pregnancy

There is no information available regarding the use of Up & Up Deep Clean Toner during pregnancy, including safety concerns, dosage modifications, or any special precautions. Healthcare professionals should exercise caution when recommending this product to pregnant patients due to the lack of data on potential risks or fetal impacts. Women of childbearing potential should be informed of the absence of specific pregnancy-related information and encouraged to discuss any concerns with their healthcare provider.

Lactation

There are no specific warnings or recommendations regarding nursing mothers or lactation in the provided text. Therefore, healthcare professionals should consider the absence of data when advising lactating mothers about the use of this medication. It is advisable to monitor breastfed infants for any potential effects, although no specific information is available.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in clinical trials for this medication. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be warranted based on clinical judgment.

Overdosage

In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.

It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.

In the event of an overdose, immediate medical attention should be sought. Healthcare providers should implement supportive care measures, which may include maintaining airway patency, providing supplemental oxygen, and monitoring vital signs.

Additionally, it is recommended to consult local poison control centers or relevant toxicology resources for guidance on specific management protocols and antidotes, if applicable.

Documentation of the incident, including the substance involved, estimated dose, and time of exposure, is crucial for effective management and follow-up care.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Patients should be advised to seek immediate medical assistance or contact a Poison Control Center if the medication is swallowed.

Healthcare providers should inform patients that the use of this medication in conjunction with other topical acne treatments may increase the likelihood of skin irritation and dryness. It is recommended that patients use only one topical acne medication at a time to minimize the risk of irritation.

Patients must be cautioned to avoid contact with the eyes. In the event of accidental contact, they should flush the eyes thoroughly with water and seek medical attention if irritation persists.

Storage and Handling

The product is supplied in various configurations, with specific NDC numbers available for identification. It is important to note that the product may stain some fabrics, and care should be taken to avoid contact with such materials.

For optimal storage, the product should be kept in a controlled environment, away from direct sunlight and extreme temperatures. It is recommended to store the product at room temperature, ensuring that it is protected from moisture and humidity. Special handling precautions should be observed to maintain the integrity of the product and to prevent any potential staining of surfaces or fabrics.

Additional Clinical Information

The medication is administered topically, with a recommended application of a thin layer to the entire affected area one to three times daily. Clinicians should advise patients to start with one application per day, gradually increasing to two or three times daily as needed or directed by a healthcare provider. In cases where bothersome dryness or peeling occurs, patients should reduce the frequency of application to once daily or every other day.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Up and up, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)