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Crest

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Active ingredient
Sodium Fluoride 1.5 mg/1 g
Other brand names
Dosage form
Paste, Dentifrice
Route
Dental
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2015
Label revision date
February 12, 2026
Active ingredient
Sodium Fluoride 1.5 mg/1 g
Other brand names
Dosage form
Paste, Dentifrice
Route
Dental
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2015
Label revision date
February 12, 2026
Manufacturer
The Procter & Gamble Manufacturing Company
Registration number
M021
NDC root
37000-868

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If you are a consumer or patient please visit this version.

Drug Overview

Crest® is a fluoride anticavity toothpaste designed to help protect your teeth against cavities. In addition to its cavity-fighting properties, it also cleans and whitens your teeth, leaving your mouth feeling fresh with its peppermint flavor. Crest® is available in a convenient 68 g tube, making it easy to incorporate into your daily oral hygiene routine.

Uses

You can use this product to help protect your teeth against cavities. It works by strengthening your enamel and creating a barrier that helps prevent decay.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with this product. This makes it a safe option for maintaining your dental health.

Dosage and Administration

It's important to take care of your teeth, and using the right toothpaste can help. If you are an adult or a child aged 2 years and older, you should brush your teeth thoroughly after meals or at least twice a day. Make sure to follow any specific instructions given by your dentist. Remember, do not swallow the toothpaste. For children under 6, use only a pea-sized amount to help minimize the chance of swallowing.

If you have a child under 2 years old, it's best to consult with a dentist before using any toothpaste. Additionally, it's a good idea to supervise your child's brushing until they develop good habits on their own. Taking these steps will help ensure that you and your family maintain healthy teeth and gums.

What to Avoid

It's important to keep this product out of reach of children under 6 years old to ensure their safety. If a child accidentally swallows more than what is typically used for brushing, seek medical help or contact a Poison Control Center immediately. This precaution helps prevent any potential harm. Always use the product as directed to ensure safe and effective use.

Side Effects

It's important to keep this product out of reach of children under 6 years old. If a child accidentally swallows more than what is typically used for brushing, seek medical help or contact a Poison Control Center immediately.

Always be aware of how to use this product safely to avoid any potential risks.

Warnings and Precautions

It's important to keep this product out of reach of children under 6 years old to prevent accidental ingestion. If a child accidentally swallows more than what is typically used for brushing, seek medical help or contact a Poison Control Center immediately.

Always use this product as directed. If you experience any unusual symptoms or reactions, stop using it and call your doctor for further advice. Your safety is a priority, so don’t hesitate to reach out for help if needed.

Overdose

If you accidentally swallow more of this product than what is typically used for brushing your teeth, it’s important to seek medical help immediately or contact a Poison Control Center. This is crucial to ensure your safety and receive the appropriate care.

Signs of an overdose may not be obvious, but if you experience any unusual symptoms after swallowing too much, don’t hesitate to reach out for assistance. Remember, it’s always better to be cautious when it comes to your health.

Pregnancy Use

When it comes to using Crest Fresh and White sodium fluoride paste during pregnancy, there is no specific information available regarding its safety, dosage adjustments, or any special precautions you should take. This means that the manufacturer has not provided guidance on how this product may affect you or your developing baby.

If you are pregnant or planning to become pregnant, it's always a good idea to consult with your healthcare provider before using any new dental products. They can help you make informed decisions based on your individual health needs and circumstances.

Lactation Use

You can feel reassured that there are no specific warnings or considerations regarding breastfeeding when using Crest Fresh and White sodium fluoride paste, dentifrice. This means that, based on the information available, it is generally considered safe for nursing mothers to use this toothpaste without concerns about affecting your breast milk or your nursing infant. Always consult with your healthcare provider if you have any specific questions or concerns about your dental care while breastfeeding.

Pediatric Use

It's important to keep this product out of reach of children under 6 years old. If your child accidentally swallows more than what is typically used for brushing, seek medical help or contact a Poison Control Center immediately. For children aged 2 years and older, encourage them to brush their teeth thoroughly after meals or at least twice a day, following your dentist's advice.

When helping younger children brush, use only a pea-sized amount to reduce the risk of swallowing, and supervise them until they develop good brushing habits. If your child is under 2 years old, consult with a dentist before using this product.

Geriatric Use

While there is no specific information about the use of Crest Fresh and White sodium fluoride paste for older adults, it’s always important to approach any new dental product with caution. If you or a loved one is considering using this toothpaste, it’s a good idea to consult with a healthcare provider, especially if there are any existing health concerns or medications involved.

Since the drug insert does not mention any dosage adjustments or special precautions for elderly patients, you can generally use it as directed on the packaging. However, staying informed and discussing any potential risks or benefits with a dentist or doctor can help ensure safe and effective use.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines, dosage adjustments, or monitoring requirements mentioned for your condition in the provided information. This means that the standard recommendations for medication use may apply to you, but it's always best to consult with your healthcare provider for personalized advice. They can help ensure that any medications you take are safe and effective for your specific health needs.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for your treatment, discussing your full medical history and any other medications is crucial. This ensures that your healthcare provider can give you the best advice tailored to your needs and help avoid any potential issues. Always feel free to ask questions and share any concerns you might have.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and avoid freezing it. When not in use, make sure to keep the tube tightly closed to maintain its integrity. If you open the product but do not use it within a certain period, it is important to discard it to ensure safety and effectiveness. Always follow these guidelines to handle the product safely and effectively.

Additional Information

You will use this medication through a dental route, which means it is applied in the mouth rather than taken by swallowing. It's important not to swallow the medication. If you are using it for children under 6, use only a pea-sized amount to help minimize swallowing. Additionally, make sure to supervise children's brushing until they develop good habits.

There is no further information available regarding laboratory tests, abuse potential, or postmarketing experiences related to this medication.

FAQ

What is Crest®?

Crest® is a fluoride anticavity toothpaste that helps protect against cavities.

How should I use Crest®?

Adults and children 2 years and older should brush their teeth thoroughly after meals or at least twice a day, or use as directed by a dentist. Children under 2 years should ask a dentist.

What precautions should I take when using Crest®?

Do not swallow Crest®. To minimize swallowing, use a pea-sized amount for children under 6 and supervise their brushing until good habits are established.

Are there any contraindications for using Crest®?

No contraindications are listed for Crest®.

What should I do if Crest® is accidentally swallowed?

If more than the amount used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Is Crest® safe for use during pregnancy or breastfeeding?

The drug insert does not provide specific information regarding safety concerns or precautions for use during pregnancy or breastfeeding.

How should I store Crest®?

Store Crest® at room temperature, do not freeze, and keep the tube tightly closed when not in use.

What flavor does Crest® come in?

Crest® is available in a peppermint flavor.

Packaging Info

Below are the non-prescription pack sizes of Crest (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Crest.
Details

Drug Information (PDF)

This file contains official product information for Crest, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the protection against cavities.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Adults and children aged 2 years and older are advised to brush their teeth thoroughly after meals or at least twice daily, or as directed by a dentist. It is important to ensure that the product is not swallowed. To minimize the risk of swallowing, a pea-sized amount should be used for children under 6 years of age. Caregivers should supervise the brushing of children's teeth until proper oral hygiene habits are established.

For children under 2 years of age, it is recommended to consult a dentist for appropriate guidance on dental care and product use.

Contraindications

Use is contraindicated in children under 6 years of age. Due to the potential risk of accidental ingestion, if more than the recommended amount for brushing is swallowed, seek medical assistance or contact a Poison Control Center immediately.

Warnings and Precautions

It is imperative to keep this product out of the reach of children under 6 years of age to prevent accidental ingestion and potential harm.

In the event that more than the recommended amount used for brushing is accidentally swallowed, immediate medical assistance should be sought. Healthcare professionals are advised to contact a Poison Control Center without delay to ensure appropriate management and care.

Side Effects

Patients should be advised to keep this product out of reach of children under 6 years of age. In the event that more than the recommended amount used for brushing is accidentally swallowed, it is imperative to seek medical assistance or contact a Poison Control Center immediately.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Crest (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Crest.
Details

Pediatric Use

Pediatric patients under 6 years of age should be supervised during brushing to establish good oral hygiene habits. It is recommended that a pea-sized amount of the product be used to minimize swallowing in this age group. For children aged 2 years and older, it is advised to brush teeth thoroughly after meals or at least twice a day, or as directed by a dentist.

Parents and caregivers should keep the product out of reach of children under 6 years. In the event that more than the recommended amount is accidentally swallowed, medical assistance or contact with a Poison Control Center should be sought immediately. For children under 2 years of age, consultation with a dentist is recommended prior to use.

Geriatric Use

There is no specific information regarding the use of Crest Fresh and White sodium fluoride paste, dentifrice in geriatric patients. The prescribing information does not provide details on dosage adjustments, safety concerns, or special precautions that may be necessary for elderly patients. Therefore, healthcare providers should exercise clinical judgment when considering the use of this product in the geriatric population, as individual patient factors may influence treatment decisions. Monitoring for any adverse effects or changes in efficacy may be warranted in this demographic.

Pregnancy

There is no specific information regarding the use of Crest Fresh and White sodium fluoride paste, dentifrice during pregnancy. The prescribing information does not provide safety concerns, dosage modifications, or special precautions for pregnant patients. Therefore, healthcare professionals should exercise caution and consider the lack of data when advising women of childbearing potential regarding the use of this product during pregnancy.

Lactation

There are no specific warnings or considerations regarding nursing mothers or lactation associated with the use of Crest Fresh and White sodium fluoride paste, dentifrice. The available data does not indicate any known effects on breastfed infants or excretion in breast milk. Therefore, lactating mothers may use this product without specific concerns related to breastfeeding.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, it is critical to seek immediate medical assistance or contact a Poison Control Center if an amount exceeding that typically used for brushing is accidentally ingested.

Healthcare professionals should be aware that prompt intervention is essential in managing potential overdosage scenarios. Symptoms may vary depending on the specific substance involved, and monitoring for adverse effects is recommended.

Management procedures should include supportive care and symptomatic treatment as necessary. It is advisable to provide the patient with information regarding the amount ingested and the time of ingestion to facilitate appropriate medical response.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are provided in the insert for CREST FRESH AND WHITE - sodium fluoride paste, dentifrice.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children under 6 years of age to prevent accidental ingestion. It is important to emphasize the potential risks associated with misuse.

In the event that more than the recommended amount used for brushing is accidentally swallowed, healthcare providers should instruct patients to seek medical help or contact a Poison Control Center immediately. This guidance is crucial for ensuring patient safety and prompt response in case of an emergency.

Storage and Handling

The product is supplied in a tube that must be stored at room temperature. It is essential to avoid freezing the product to maintain its integrity. To ensure optimal performance, the tube should be kept tightly closed when not in use. Additionally, any unused product should be discarded after opening if it is not utilized within a specified period, which is not detailed in the provided information.

Additional Clinical Information

The product is administered via the dental route. Clinicians should advise patients not to swallow the product. For children under the age of 6, it is recommended to use a pea-sized amount to minimize swallowing, and caregivers should supervise children's brushing until proper oral hygiene habits are established.

Drug Information (PDF)

This file contains official product information for Crest, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Crest, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.