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Target Childrens Cough Relief

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Active ingredients
  • Guaifenesin 100 mg/5 mL
  • Dextromethorphan Hydrobromide 5 mg/5 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
November 5, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Guaifenesin 100 mg/5 mL
  • Dextromethorphan Hydrobromide 5 mg/5 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
November 5, 2025
Manufacturer
TARGET CORPORATION
Registration number
M012
NDC root
82442-751
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Children's Cough Relief is a medication designed for children aged 4 years and older, formulated to help alleviate coughs and chest congestion. It contains two active ingredients: Dextromethorphan HBr, which helps control the impulse to cough, and Guaifenesin, which works to loosen phlegm (mucus) and thin bronchial secretions. This combination makes coughs more productive by clearing mucus from the bronchial passageways.

This product temporarily relieves cough caused by minor throat and bronchial irritation, which can occur with common colds or from inhaled irritants. Additionally, it helps reduce the intensity of coughing, making it easier for your child to sleep. With a pleasant natural cherry flavor, Children's Cough Relief aims to provide comfort during times of illness.

Uses

This medication is designed to help you breathe easier by loosening phlegm (mucus) and thinning bronchial secretions. This action helps clear out bothersome mucus from your airways, making your coughs more productive.

It can temporarily relieve coughs caused by minor throat and bronchial irritation, which may happen due to the common cold or exposure to irritants in the air. Additionally, it can reduce the intensity of your cough and help lessen the urge to cough, making it easier for you or your child to get a good night's sleep.

Dosage and Administration

When using this medication, it's important to follow the dosing guidelines carefully to ensure safety and effectiveness. You should never give more than 6 doses within a 24-hour period. To measure the correct amount, always use the dosing cup that comes with the medication, and avoid using it for any other products to prevent confusion.

For children aged 6 years to under 12 years, the recommended dose is between 5 mL and 10 mL every 4 hours. If your child is between 4 years and under 6 years, the dose should be between 2.5 mL and 5 mL every 4 hours. Please remember that this medication is not suitable for children under 4 years of age. Always consult with a doctor if you have any questions or concerns about the appropriate dosage for your child.

What to Avoid

It’s important to be cautious when considering this medication for your child. You should not use it if your child is currently taking a prescription monoamine oxidase inhibitor (MAOI), which are specific medications for depression, psychiatric conditions, or Parkinson's disease. Additionally, you must wait at least two weeks after stopping an MAOI before using this product. If you're unsure whether your child's medication includes an MAOI, please consult a doctor or pharmacist.

Always follow the dosing instructions carefully and do not exceed the recommended amount. Misuse or taking more than directed can lead to serious issues, including dependence (a condition where the body becomes reliant on a substance). Your child's safety is the top priority, so please adhere to these guidelines.

Side Effects

It's important to be aware of potential side effects when using this product. You should not give it to a child who is currently taking a monoamine oxidase inhibitor (MAOI) or has taken one in the past two weeks, as this can lead to serious interactions. If your child's cough lasts more than seven days, returns, or is accompanied by fever, rash, or a persistent headache, stop using the product and consult a doctor, as these may indicate a more serious condition.

Before using this product, consult a doctor if your child has a cough with excessive mucus or a chronic cough, such as one associated with asthma. Always keep the product out of reach of children, and in case of an overdose, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

Warnings and Precautions

You should not give this medication to a child who is currently taking a prescription monoamine oxidase inhibitor (MAOI), which is a type of medication used for depression, certain psychiatric conditions, or Parkinson's disease. Additionally, do not use it for at least two weeks after stopping an MAOI. If you're unsure whether your child's medication contains an MAOI, please consult a doctor or pharmacist.

Before using this product, it's important to ask a doctor if your child has a cough that produces a lot of mucus or a persistent cough, such as one associated with asthma. If the cough lasts more than seven days, returns, or is accompanied by a fever, rash, or a persistent headache, stop using the medication and contact a doctor, as these may indicate a more serious issue.

Always keep this medication out of reach of children. In the event of an overdose, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

Overdose

If you suspect an overdose, it’s crucial to seek medical help immediately. You can contact a Poison Control Center at 1-800-222-1222 for guidance. Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing.

Always err on the side of caution—if you notice any concerning symptoms or if you’re unsure, don’t hesitate to get help right away. Your safety is the top priority.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that the safety of this product during pregnancy has not been established. You should consult your doctor before using it, as there may be potential risks to your fetus, and further studies are needed to fully understand these risks.

Currently, there are no specific dosage modifications recommended for pregnant individuals, so it's essential to seek guidance from a healthcare professional regarding its use. Always prioritize your health and the health of your baby by discussing any medications with your doctor.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks it may pose to your infant.

As always, if you have any concerns or questions about using this product while breastfeeding, it's a good idea to consult with your healthcare provider for personalized advice.

Pediatric Use

It's important to be cautious when giving medication to children. You should not use this medication if your child is currently taking a prescription monoamine oxidase inhibitor (MAOI) or has taken one in the past two weeks. Before using it, consult your doctor if your child has a cough with excessive mucus or a persistent cough, such as one caused by asthma.

When administering the medication, make sure to follow the dosing guidelines carefully. For children aged 6 to under 12 years, the recommended dose is 5 mL to 10 mL every 4 hours, while for those aged 4 to under 6 years, the dose is 2.5 mL to 5 mL every 4 hours. Children under 4 years should not use this medication at all. Remember to measure the dose using the provided dosing cup and do not exceed 6 doses in a 24-hour period.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if your kidneys are not functioning properly.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your kidney health. They can help monitor your condition and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication should be used if you have hepatic impairment (issues with liver function).

Before starting any new medication, including this one, you should discuss your liver health with your healthcare provider. They can help determine the best approach for your treatment and ensure your safety.

Drug Interactions

It's important to be cautious when it comes to medications, especially if you or your child are taking certain drugs. For instance, if your child is on a prescription monoamine oxidase inhibitor (MAOI), a type of medication used to treat depression, you should avoid using this drug while they are taking the MAOI and for at least two weeks after stopping it. This is crucial because combining these medications can lead to serious interactions that may affect your child's health.

Always discuss any medications or treatments with your healthcare provider to ensure safety and effectiveness. They can help you understand potential risks and make informed decisions about your or your child's health.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. It's important to avoid refrigerating it, as this can affect its effectiveness. When handling the product, make sure to do so with clean hands and in a clean environment to maintain its integrity and safety. Always follow these guidelines to ensure you are using the product correctly and safely.

Additional Information

You will take this medication orally. There are no additional details available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experiences. If you have any questions or concerns about your treatment, be sure to discuss them with your healthcare provider.

FAQ

What is Children's Cough Relief?

Children's Cough Relief is a medication that contains Dextromethorphan HBr 5 mg and Guaifenesin 100 mg, designed to help relieve cough and chest congestion in children aged 4 years and older.

How does Children's Cough Relief work?

It helps loosen phlegm (mucus) and thin bronchial secretions, making coughs more productive and temporarily relieving cough due to minor throat and bronchial irritation.

What are the dosing instructions for Children's Cough Relief?

For children 6 years to under 12 years, the dose is 5 mL – 10 mL every 4 hours. For children 4 years to under 6 years, the dose is 2.5 mL – 5 mL every 4 hours. Do not use in children under 4 years.

Are there any contraindications for using this product?

Do not use Children's Cough Relief in a child who is taking a prescription monoamine oxidase inhibitor (MAOI) or for 2 weeks after stopping an MAOI.

What should I do if my child's cough lasts more than 7 days?

Stop use and ask a doctor if the cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache, as these could be signs of a serious condition.

Is it safe to use Children's Cough Relief during pregnancy?

The safety of this product during pregnancy has not been established, so consult a doctor before use if pregnant or planning to become pregnant.

What flavor does Children's Cough Relief have?

Children's Cough Relief has a natural cherry flavor.

How should I store Children's Cough Relief?

Store Children's Cough Relief at room temperature and do not refrigerate.

What should I do in case of an overdose?

In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

Packaging Info

Below are the non-prescription pack sizes of Target Childrens Cough Relief (dextromethorphan hydrobromide and guaifenesin). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Target Childrens Cough Relief.
Details

Drug Information (PDF)

This file contains official product information for Target Childrens Cough Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of cough associated with minor throat and bronchial irritation, which may occur due to the common cold or inhaled irritants. It aids in loosening phlegm (mucus) and thinning bronchial secretions, thereby facilitating the clearance of mucus from the bronchial passageways and making coughs more productive.

Additionally, this drug temporarily relieves the intensity of coughing and the impulse to cough, which can assist children in achieving restful sleep.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

The maximum recommended dosage is six doses within a 24-hour period. Dosing should be measured exclusively with the dosing cup provided with the product; the use of this cup with other products is not advised.

For children aged 6 years to under 12 years, the recommended dose is 5 mL to 10 mL administered every 4 hours as needed. For children aged 4 years to under 6 years, the appropriate dose is 2.5 mL to 5 mL every 4 hours as needed. The product is not recommended for use in children under 4 years of age.

Healthcare professionals should ensure that dosing adheres strictly to these guidelines or as directed by a physician.

Contraindications

Use of this product is contraindicated in children who are currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of discontinuing an MAOI. MAOIs are typically prescribed for depression, psychiatric or emotional conditions, or Parkinson's disease. If there is uncertainty regarding the presence of an MAOI in a child's prescription medication, consultation with a healthcare professional is advised prior to administration of this product. Additionally, it is contraindicated to exceed the recommended dosage while using this product.

Warnings and Precautions

Use of this product is contraindicated in children who are currently taking a prescription monoamine oxidase inhibitor (MAOI), which includes certain medications prescribed for depression, psychiatric or emotional conditions, or Parkinson's disease. Additionally, this product should not be administered for a period of 2 weeks following the discontinuation of an MAOI. If there is uncertainty regarding whether a child's prescription includes an MAOI, it is imperative to consult a healthcare professional, such as a doctor or pharmacist, prior to administration.

Healthcare professionals should advise caregivers to seek medical guidance before using this product if the child presents with a cough that is accompanied by excessive phlegm (mucus) or if the child has a persistent or chronic cough, such as that associated with asthma.

In the event that the cough persists for more than 7 days, recurs, or is accompanied by additional symptoms such as fever, rash, or a persistent headache, it is crucial to discontinue use and consult a healthcare provider. These symptoms may indicate a serious underlying condition that requires further evaluation.

To ensure safety, this product must be kept out of reach of children. In the case of an overdose, immediate medical assistance should be sought, or the Poison Control Center should be contacted at 1-800-222-1222.

Side Effects

Patients should be aware of the following adverse reactions and important safety information associated with the use of this product.

Serious adverse reactions may occur, particularly in children who are concurrently taking a prescription monoamine oxidase inhibitor (MAOI) or have taken one within the past two weeks. It is crucial to consult a healthcare professional if there is uncertainty regarding the presence of an MAOI in the child's prescription medication.

Common adverse reactions include the need to stop use and seek medical advice if a cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or a persistent headache, as these symptoms may indicate a serious underlying condition.

Before using this product, it is advisable to consult a healthcare provider if the child has a cough that produces excessive phlegm or if the cough is persistent or chronic, such as that associated with asthma.

Additionally, it is important to keep this product out of reach of children. In the event of an overdose, immediate medical assistance should be sought, or contact a Poison Control Center at 1-800-222-1222.

Drug Interactions

The use of this medication is contraindicated in pediatric patients who are concurrently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of discontinuing an MAOI. Co-administration may result in serious interactions that could pose significant health risks.

No additional drug interactions or laboratory test interactions have been identified for this medication. Therefore, no further dosage adjustments or monitoring recommendations are necessary beyond the stated contraindication.

Packaging & NDC

Below are the non-prescription pack sizes of Target Childrens Cough Relief (dextromethorphan hydrobromide and guaifenesin). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Target Childrens Cough Relief.
Details

Pediatric Use

Pediatric patients should not use this medication if they are currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of stopping an MAOI. Prior to administration, it is advisable to consult a healthcare professional if the child has a cough associated with excessive phlegm or a persistent cough, such as that which occurs with asthma.

For dosing, the following guidelines should be adhered to, or as directed by a healthcare provider:

  • For children aged 6 years to under 12 years, the recommended dose is 5 mL to 10 mL every 4 hours.

  • For children aged 4 years to under 6 years, the recommended dose is 2.5 mL to 5 mL every 4 hours.

  • This medication is not recommended for children under 4 years of age.

It is important to not exceed 6 doses in any 24-hour period. The medication should be measured using the dosing cup provided, and this cup should not be used with other products to ensure accurate dosing.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

The safety of this product during pregnancy has not been established. Pregnant patients or those planning to become pregnant should consult a healthcare professional before use, as there may be potential risks to the fetus. Further studies are needed to determine the safety profile of this product in pregnant individuals. Currently, no specific dosage modifications are provided for pregnant individuals; therefore, it is essential to seek guidance from a healthcare professional regarding the use of this product during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the drug insert text regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the lack of data necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients, although specific recommendations are not provided.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdose, it is imperative to seek immediate medical assistance. Healthcare professionals are advised to contact a Poison Control Center without delay. The national helpline for poison control can be reached at 1-800-222-1222.

Prompt intervention is crucial in managing potential overdose situations. Symptoms may vary depending on the substance involved, and healthcare providers should be prepared to assess and address any clinical manifestations that arise.

Management procedures should include a thorough evaluation of the patient's condition, monitoring vital signs, and providing supportive care as necessary. It is essential to follow established protocols for overdose management, which may involve decontamination, administration of antidotes, or other therapeutic measures based on the specific circumstances of the overdose.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the understanding of potential risks associated with the compound in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the provided data.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. In the event of an overdose, patients should be instructed to seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

It is crucial to inform patients that this product should not be used in children who are currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of stopping such medication. Patients should be encouraged to consult with a doctor or pharmacist if they are uncertain whether their child's prescription includes an MAOI.

Patients should be instructed to discontinue use and consult a doctor if a cough persists for more than 7 days, returns, or is accompanied by fever, rash, or a persistent headache, as these symptoms may indicate a serious condition.

While using this product, patients must be reminded not to exceed the recommended dosage. Additionally, healthcare providers should advise patients to seek medical advice before use if the child has a cough associated with excessive phlegm (mucus) or if the cough is persistent or chronic, such as that which occurs with asthma.

Storage and Handling

The product is supplied in configurations that include specific NDC numbers. It should be stored at room temperature, ensuring that it is not exposed to refrigeration. Proper handling is essential to maintain the integrity of the product, and it is important to adhere to these storage conditions to ensure optimal efficacy.

Additional Clinical Information

The medication is administered orally. There are no additional details available regarding laboratory tests, abuse information, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Target Childrens Cough Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Target Childrens Cough Relief, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.