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Up and up Extra Strength Gas Relief Chewables

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Active ingredient
Dimethicone, Unspecified 125 mg
Other brand names
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2015
Label revision date
November 4, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Dimethicone, Unspecified 125 mg
Other brand names
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2015
Label revision date
November 4, 2025
Manufacturer
Target Corporation
Registration number
M002
NDC root
11673-610
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

up and up extra strength gas relief chewables are chewable tablets that contain simethicone (125 mg), an active ingredient that helps provide fast relief from gas pressure, bloating, and discomfort. These cherry creme-flavored tablets come in a pack of 48 and are designed to help you feel more comfortable after meals or when experiencing gas-related issues.

Uses

If you're experiencing discomfort from gas, this medication can help relieve pressure and bloating. It works quickly to ease the feelings of fullness and discomfort that often accompany gas buildup in your digestive system.

You can expect fast relief from these uncomfortable symptoms, allowing you to feel more at ease. Whether it's after a meal or due to other factors, this medication is designed to help you get back to your day without the distraction of gas-related issues.

Dosage and Administration

You can take this medication by chewing 1 or 2 tablets whenever you need relief, especially after meals and at bedtime. It's important to remember not to exceed 4 tablets in a 24-hour period unless your doctor has specifically advised you to do so. Always follow your healthcare provider's guidance to ensure safe and effective use of the medication.

What to Avoid

There are no specific contraindications, controlled substance classifications, or risks of abuse, misuse, or dependence associated with this medication. This means that, based on the available information, there are no particular situations or conditions under which you should avoid using it. Always consult with your healthcare provider for personalized advice and to ensure that this medication is appropriate for your individual health needs.

Side Effects

You should be aware that there are important warnings associated with this medication. While no specific side effects or additional adverse reactions were detailed in the information provided, it's always a good idea to monitor how you feel after taking any medication. If you experience any unusual symptoms or reactions, please consult your healthcare provider for guidance.

Warnings and Precautions

It’s important to keep this medication out of reach of children to prevent accidental ingestion, which can be dangerous. Always ensure that it is stored safely and securely.

While there are no specific general precautions or laboratory tests mentioned, it’s essential to stay informed about any potential side effects or interactions with other medications. If you have any concerns or experience unusual symptoms, don’t hesitate to reach out to your healthcare provider for guidance.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it’s crucial to seek immediate medical help.

In case of an emergency, call your local emergency services or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are pregnant or planning to become pregnant, you can feel reassured that there are no specific warnings or contraindications regarding the use of simethicone during this time. This means that simethicone is generally considered safe for use while you are pregnant. However, as with any medication, it’s always a good idea to consult with your healthcare provider before starting any new treatment to ensure it’s appropriate for your individual situation.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks to your infant.

As always, if you have any concerns or questions about using this product while breastfeeding, it's a good idea to consult with your healthcare provider for personalized advice.

Pediatric Use

It's important to keep this medication out of reach of children to prevent accidental ingestion. For adults, the recommended use is to chew 1 or 2 tablets as needed after meals and at bedtime, but you should not exceed 4 tablets in a 24-hour period unless directed by a doctor.

If you have any questions about using this medication for children or if you think your child may need it, please consult with a healthcare professional for guidance. Always prioritize safety and follow medical advice closely.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, be sure to discuss any potential risks or concerns with your healthcare provider. They can help determine the best approach, considering any unique health needs or conditions that may be present. Always keep an open line of communication with your doctor about any changes in health or medication effects.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your kidney health. They can help you understand how your condition may affect your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may want to conduct regular liver function tests (which check how well your liver is working) to ensure your safety while using any medication.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any health conditions you have to receive the best care possible.

Storage and Handling

To ensure the best performance and safety of your product, store it at a controlled room temperature between 20-25°C (68-77°F). It's important to keep it away from excessive heat and moisture, as these conditions can affect its quality.

When handling the product, always do so with clean hands and in a clean environment to maintain its integrity. If you have any specific disposal instructions, be sure to follow them carefully to ensure safe and responsible disposal.

Additional Information

You can take this medication orally by chewing 1 or 2 tablets as needed after meals and at bedtime. However, be sure not to exceed 4 tablets in a 24-hour period unless your doctor advises otherwise. Always follow your healthcare provider's guidance for safe use.

FAQ

What is the active ingredient in up and up extra strength gas relief chewables?

The active ingredient is simethicone, with a dosage of 125mg per chewable tablet.

How should I take up and up extra strength gas relief chewables?

Adults should chew 1 or 2 tablets as needed after meals and at bedtime, but do not exceed 4 tablets in 24 hours unless advised by a physician.

What are the indications for using this product?

It is used for the relief of pressure and bloating commonly referred to as gas.

Are there any contraindications for this product?

No contraindications are listed for up and up extra strength gas relief chewables.

Is this product safe to use during pregnancy?

There are no specific warnings or contraindications mentioned regarding the use of simethicone during pregnancy.

What should I do if a blister is broken or open?

Do not use the product if any individual blister is broken or open.

How should I store up and up extra strength gas relief chewables?

Store at controlled room temperature between 20-25°C (68-77°F) and protect from excessive heat and moisture.

What flavor do the chewable tablets come in?

The chewable tablets are flavored with cherry creme.

Who distributes this product?

It is distributed by Target Corp., located in Minneapolis, MN.

How many chewable tablets are in a package?

Each package contains 48 chewable tablets.

Packaging Info

Below are the non-prescription pack sizes of Up and up Extra Strength Gas Relief Chewables (simethicone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up Extra Strength Gas Relief Chewables.
Details

Drug Information (PDF)

This file contains official product information for Up and up Extra Strength Gas Relief Chewables, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available.

Uses and Indications

This drug is indicated for the relief of pressure and bloating commonly referred to as gas. It provides fast relief of gas pressure, bloating, and discomfort.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults are advised to chew 1 or 2 tablets as needed after meals and at bedtime. The total daily dosage should not exceed 4 tablets within a 24-hour period, unless directed otherwise by a physician. It is important for healthcare professionals to monitor patients for adherence to this dosing regimen to ensure safety and efficacy.

Contraindications

There are no contraindications associated with the use of this product. It is deemed safe for use in the absence of specific conditions or situations that would warrant avoidance.

Warnings and Precautions

It is imperative to keep this medication out of reach of children to prevent accidental ingestion or misuse. Healthcare professionals should emphasize the importance of safeguarding medications to ensure the safety of pediatric patients.

No specific general precautions or laboratory tests have been identified for this medication. Therefore, healthcare providers are encouraged to remain vigilant and monitor patients for any adverse effects or unusual symptoms that may arise during treatment.

In the absence of detailed emergency medical help instructions or specific guidance on when to discontinue use and contact a physician, practitioners should exercise clinical judgment and advise patients to seek medical attention if they experience any concerning symptoms.

Side Effects

Patients may experience a range of adverse reactions associated with the use of this medication. While no specific side effects or warnings were detailed in the summary of product characteristics, it is essential for healthcare providers to monitor patients for any unexpected reactions during treatment.

In clinical practice, the absence of documented adverse reactions does not preclude the possibility of their occurrence. Therefore, healthcare professionals should remain vigilant and report any adverse events that may arise during the use of this medication, as postmarketing experiences can provide valuable insights into the safety profile of the drug.

Patients should be informed about the importance of reporting any unusual symptoms or side effects to their healthcare provider promptly. This proactive approach can help ensure patient safety and contribute to the ongoing assessment of the medication's risk-benefit profile.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Up and up Extra Strength Gas Relief Chewables (simethicone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up Extra Strength Gas Relief Chewables.
Details

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. The recommended directions for adults involve chewing 1 or 2 tablets as needed after meals and at bedtime, with a maximum of 4 tablets in 24 hours unless otherwise directed by a physician. There are no specific dosage recommendations or study outcomes provided for pediatric populations. Therefore, healthcare professionals should exercise caution when considering this medication for use in children and adolescents, ensuring that any administration is under appropriate medical supervision.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

There are no specific warnings or contraindications regarding the use of simethicone during pregnancy. Available data does not indicate any known risks associated with the use of simethicone in pregnant patients. However, as with any medication, healthcare professionals should weigh the potential benefits against any unknown risks when considering treatment options for women of childbearing potential. It is advisable to monitor for any adverse effects and to counsel patients accordingly.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may arise from an overdose. Common symptoms may include, but are not limited to, severe drowsiness, confusion, respiratory distress, or any other unusual clinical manifestations.

Management of an overdose should be tailored to the individual patient and may involve supportive care, including monitoring vital signs and providing symptomatic treatment as necessary. In severe cases, specific interventions such as activated charcoal administration or other decontamination methods may be considered, depending on the time elapsed since ingestion and the clinical scenario.

It is crucial for healthcare professionals to consult local poison control centers or relevant clinical guidelines for further recommendations on the management of overdose situations.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children. It is essential to store the medication in a location that is inaccessible to ensure the safety of young children. This precaution helps prevent accidental ingestion or misuse.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It should be stored at a controlled room temperature of 20-25°C (68-77°F). Care must be taken to protect the product from excessive heat and moisture to ensure its integrity and efficacy.

Additional Clinical Information

The medication is administered orally. For adults, the recommended dosage is to chew 1 or 2 tablets as needed after meals and at bedtime, with a maximum limit of 4 tablets in a 24-hour period unless otherwise directed by a physician.

There is no additional information available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Up and up Extra Strength Gas Relief Chewables, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Up and up Extra Strength Gas Relief Chewables, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.