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Up and up Pain

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This product has been discontinued

Active ingredients
  • Camphor (synthetic) 12 mg
  • Menthol 57 mg
  • Methyl Salicylate 63 mg
Other brand names
Dosage form
Patch
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
December 20, 2024
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Camphor (synthetic) 12 mg
  • Menthol 57 mg
  • Methyl Salicylate 63 mg
Other brand names
Dosage form
Patch
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
December 20, 2024
Manufacturer
Target Corporation
Registration number
M017
NDC root
82442-213
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

You may be looking for a medication that is designed to be applied to the skin to help with certain conditions. This drug is typically used for adults and children aged 12 years and older, and it works by being placed on the affected area of the skin. It is important to clean and dry the area before applying the patch, and it should not be worn for more than 4 hours at a time.

If you are considering this treatment for a child under 12, it is best to consult a doctor for guidance. Always follow the specific instructions provided for the best results.

Uses

You can use this medication to help treat certain skin conditions for both adults and children aged 12 years and older. To apply, make sure to clean and dry the affected area first. You should apply the medication no more than 3 to 4 times a day, and remember to remove the patch from its film before putting it on your skin. It's important not to wear the patch for more than 4 hours at a time.

If you have a child under 12 years old who may need this treatment, it's best to consult a doctor before use. There are no specific concerns regarding teratogenic effects (which refer to substances that can cause birth defects) or nonteratogenic effects noted for this medication.

Dosage and Administration

It seems that there are no specific dosage or administration details available for this medication. This means that you should consult your healthcare provider for personalized instructions on how to take or apply it. They will provide you with the necessary information regarding the correct amount, how to use it, and how often you should do so. Always follow their guidance to ensure safe and effective use of the medication.

What to Avoid

It's important to use this product safely to avoid potential issues. Do not apply it to wounds or damaged skin, and avoid using it with a heating pad. If you are allergic to any of the ingredients, do not use this product. Additionally, it should not be used on children under 12 years of age who have arthritis-like conditions.

Make sure to follow these guidelines: use the product only as directed, and keep it away from your eyes, mucous membranes, and any rashes. Avoid wrapping the area tightly, and stop using it at least one hour before taking a bath or shower. Lastly, do not apply it immediately after bathing or showering.

Side Effects

If you are considering using this product, please note that it is for external use only. If you have a history of allergic reactions to aspirin or salicylates, it’s important to consult your doctor before using it.

You should stop using the product and contact your doctor if you notice any redness, irritation, or rash developing, if your condition worsens, or if symptoms persist for more than seven days. Additionally, if your symptoms improve and then return within a few days, seek medical advice. If you have redness over the affected area, it’s also advisable to consult a doctor before use.

Warnings and Precautions

This product is for external use only. If you have a history of allergic reactions to aspirin or salicylates, please consult your doctor before using it.

If you accidentally swallow the product, seek emergency medical help immediately or contact a Poison Control Center at 1-800-222-1222. You should also stop using the product and call your doctor if you notice any redness, irritation, or rash, if your condition worsens, or if your symptoms last longer than 7 days. Additionally, if your symptoms improve and then return within a few days, it's important to reach out to your doctor.

Overdose

If you suspect an overdose, it's important to stay calm and take immediate action. While there is no specific information available about the effects of an overdose for this medication, you should be aware of general signs that may indicate a problem. These can include unusual drowsiness, confusion, or difficulty breathing.

If you notice any of these symptoms or have concerns about a possible overdose, seek medical help right away. Contact your healthcare provider or go to the nearest emergency room. It's always better to be safe and get checked out if you think you may have taken too much of a medication.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

It's important to be cautious when considering this medication for children. If your child is under 12 years old and has arthritis-like conditions, you should not use this medication. For any child under 12, it's best to consult a doctor before starting treatment to ensure it's safe and appropriate for their specific situation. Always prioritize your child's health by seeking professional guidance.

Geriatric Use

You can feel reassured that there are no specific concerns or special precautions for older adults when using the UP AND UP PAIN patch, which contains camphor, menthol, and methyl salicylate. The information provided does not indicate any need for dosage adjustments or safety issues specifically related to elderly patients.

As always, it's a good idea to consult with a healthcare professional if you have any questions or concerns about using this product, especially if you are managing other health conditions or medications.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

If you have a history of allergic reactions to aspirin or salicylates, it's important to talk to your doctor before using this medication. Allergies can lead to serious health issues, and your healthcare provider can help determine the best course of action for you.

Additionally, there are no specific interactions with other drugs or laboratory tests noted, but it's always a good practice to discuss all medications and tests with your healthcare provider. This ensures your safety and helps manage your overall health effectively.

Storage and Handling

To ensure the best performance of your product, store it at room temperature, ideally between 20-25°C (68-77°F). It's important to keep it away from direct sunlight, as exposure can affect its quality. Additionally, protect the product from excessive moisture, which can also compromise its effectiveness.

When handling the product, always do so with clean hands and in a clean environment to maintain its integrity. Following these simple guidelines will help you use the product safely and effectively.

Additional Information

You should apply this medication topically to the affected area no more than 3 to 4 times a day. Remember not to wear the patch for more than 4 hours at a time. If you are pregnant or breastfeeding, it's important to consult a healthcare professional before using this product.

Keep the medication out of reach of children. If a child accidentally swallows it, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

FAQ

How should I use the patch?

Clean and dry the affected area, remove the patch from the film, and apply it no more than 3 to 4 times daily. Do not wear the patch for more than 4 hours.

What should I do if I am under 12 years old?

If you are under 12 years of age, consult a doctor before use.

Are there any contraindications for using this patch?

Do not use the patch on wounds or damaged skin, with a heating pad, or if you are allergic to any of its ingredients.

What should I do if I experience redness or irritation?

Stop use and ask a doctor if redness, irritation, or rash develops, or if the condition worsens or persists for more than 7 days.

Can I use this patch if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before use.

What should I do if the patch is swallowed?

Get medical help or contact a Poison Control Center (1-800-222-1222) right away if swallowed.

How should I store the patch?

Store the patch at room temperature between 20-25°C (68-77°F) and protect it from direct sunlight and excessive moisture.

Packaging Info

Below are the non-prescription pack sizes of Up and up Pain (camphor, menthol, and methyl salicylate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up Pain.
Details

Drug Information (PDF)

This file contains official product information for Up and up Pain, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

The product is identified by the SPL code 34089-3. No additional specific description details are provided in the available text.

Uses and Indications

This drug is indicated for the topical treatment of affected areas in adults and children aged 12 years and older. It should be applied no more than 3 to 4 times daily. Prior to application, the affected area must be cleaned and dried thoroughly. The patch should be removed from its film before application, and it is important not to wear the patch for more than 4 hours.

For children under 12 years of age, consultation with a healthcare professional is recommended prior to use.

No specific teratogenic or nonteratogenic effects have been identified.

Dosage and Administration

There is currently no specific dosage or administration information available for this medication. Healthcare professionals are advised to refer to the prescribing information or clinical guidelines for detailed instructions regarding the appropriate dosage, route, method, and frequency of administration. It is essential to consider individual patient factors and clinical judgment when determining the appropriate treatment regimen.

Contraindications

Use of this product is contraindicated in the following situations:

The product should not be applied to wounds or damaged skin due to the risk of irritation and impaired healing. Application with a heating pad is contraindicated as it may increase the risk of burns or skin damage. Individuals with known allergies to any ingredients in this product should avoid its use to prevent allergic reactions. Additionally, the product is not recommended for children under 12 years of age with arthritis-like conditions, as safety and efficacy have not been established in this population.

Furthermore, the product should not be used contrary to the directions provided. Contact with eyes, mucous membranes, or rashes should be avoided to prevent adverse effects. Bandaging should not be done tightly to allow for proper circulation. Discontinue use at least one hour prior to bathing or showering, and do not apply immediately after bathing or showering to minimize the risk of skin irritation.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients to consult a physician prior to use if they have a known allergy to aspirin or salicylates, as this may increase the risk of an allergic reaction.

In the event of accidental ingestion, immediate medical assistance should be sought. Patients are encouraged to contact a Poison Control Center at 1-800-222-1222 without delay.

Patients should be instructed to discontinue use and consult a healthcare provider if any of the following occur: the presence of redness, the development of irritation or rash, worsening of the condition, or if symptoms persist beyond 7 days. Additionally, if symptoms resolve and then recur within a few days, patients should seek medical advice.

Side Effects

Patients should be aware that the product is for external use only. An allergy alert is warranted; individuals who are prone to allergic reactions from aspirin or salicylates should consult a healthcare professional prior to use.

In clinical practice, patients are advised to stop using the product and seek medical attention if they experience redness, irritation, or rash. Additionally, if the condition worsens or symptoms persist for more than 7 days, it is important to consult a doctor. Patients should also be cautious if symptoms initially improve but then recur within a few days.

Before using the product, patients with redness over the affected area should consult a healthcare provider to ensure safe and appropriate use.

Drug Interactions

Patients with a known allergy to aspirin or salicylates should consult a healthcare professional prior to use, as there is a potential risk of allergic reactions.

No specific drug or laboratory test interactions have been identified in the available data. Therefore, routine monitoring or dosage adjustments related to drug interactions are not necessary.

Packaging & NDC

Below are the non-prescription pack sizes of Up and up Pain (camphor, menthol, and methyl salicylate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Up and up Pain.
Details

Pediatric Use

Pediatric patients with arthritis-like conditions under 12 years of age should not use this medication. For children in this age group, it is essential to consult a healthcare professional before administration.

Geriatric Use

Elderly patients do not have specific geriatric use considerations, dosage adjustments, safety concerns, or special precautions associated with the use of UP AND UP PAIN, which contains camphor, menthol, and methyl salicylate. As such, healthcare providers may consider the standard dosing regimen for this population without the need for modifications or additional monitoring specific to geriatric patients. However, it is always prudent to assess individual patient circumstances and overall health status when prescribing to elderly patients.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully weighed, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to seek medical advice to ensure safe use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment may not have specific information regarding dosage adjustments, special monitoring, or safety considerations outlined in the prescribing information. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment and monitoring of these patients.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific information regarding overdosage in the provided sections of the Summary of Product Characteristics (SPL), healthcare professionals are advised to exercise caution and consider general principles of management for suspected overdosage cases.

Recommended Actions In the event of an overdosage, it is essential for healthcare providers to assess the patient's clinical status promptly. Supportive care should be initiated as necessary, and symptomatic treatment should be provided based on the patient's presentation.

Potential Symptoms While specific symptoms related to overdosage are not detailed, healthcare professionals should remain vigilant for any unusual or severe reactions that may arise following administration. Monitoring for adverse effects is crucial, and any signs of toxicity should be addressed immediately.

Management Procedures Healthcare professionals are encouraged to consult local poison control centers or toxicology experts for guidance on the management of overdosage. It is important to document the incident thoroughly and report any adverse events to the appropriate regulatory authorities as per local regulations.

In summary, due to the lack of specific overdosage information, a cautious and supportive approach is recommended, with an emphasis on monitoring and managing symptoms as they arise.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in question. Further studies may be necessary to elucidate these aspects of nonclinical toxicology.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. In the event of swallowing the product, patients should seek medical help or contact a Poison Control Center immediately at 1-800-222-1222.

Patients should be instructed not to use the product on wounds or damaged skin, and to avoid using it in conjunction with a heating pad. It is important to inform patients that they should not use the product if they are allergic to any of its ingredients. Additionally, the product is not recommended for use in children under 12 years of age who have arthritis-like conditions.

Patients should be counseled to stop using the product and consult a doctor if they experience redness, irritation, or rash. They should also be advised to seek medical advice if their condition worsens or if symptoms persist for more than 7 days. If symptoms resolve and then recur within a few days, patients should discontinue use and consult a healthcare professional.

When using the product, patients must be reminded to follow the directions carefully and avoid contact with the eyes, mucous membranes, or rashes. They should not apply a tight bandage over the area of application and should discontinue use at least 1 hour before bathing or showering. Furthermore, patients should be advised against using the product immediately after bathing or showering. If there is any redness over the affected area, patients should be encouraged to consult a doctor before use.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature, within the range of 20-25°C (68-77°F). Care should be taken to avoid exposure to direct sunlight, as this may compromise the integrity of the product. Additionally, it is important to protect the product from excessive moisture to ensure its stability and efficacy.

Additional Clinical Information

The medication is administered topically, with a recommended application to the affected area no more than 3 to 4 times daily. Patients should not wear the patch for more than 4 hours at a time.

Clinicians should advise patients who are pregnant or breastfeeding to consult a health professional prior to use. Additionally, it is important to keep the medication out of reach of children; if ingested, medical assistance should be sought immediately or contact a Poison Control Center at 1-800-222-1222.

Drug Information (PDF)

This file contains official product information for Up and up Pain, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Up and up Pain, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.